Our world is increasingly disrupted by digital transformation, and the complexity of the global web of goods and services is on the rise. As we continue to automate and differentiate our supply chains to deliver new products across ever-increasing numbers of channels and configurations with ever-shortening product lifecycles, it becomes imperative to adopt new technologies to innovate across a broader range of partner ecosystems. This presentation will take a look at how smart high-tech capabilities are now being built using interesting combinations of new and disruptive technologies (including AI and Blockchain) that enable us to move from reactive to proactive, predictive, and highly orchestrated world-class supply chains. Presented at the 2019 ASCM Conference--Las Vegas, Nevada.