Understand lesson's learned from the practical deployment of AI and ML solutions in actual enterprise settings driving innovative business transformation from marketing to supply chain. Learners can use these solutions to incorporate in their own organizations to ensure the success of AI and ML initiatives. This presentation showcases how large manufacturing centric enterprises are going about laying the blueprint for transformation towards next-generation supply chain and Industries 4.0, as well as how leading-edge disruptive retailers are driving Omni-channel retail. Presented at the 2019 ASCM Conference--Las Vegas, Nevada.